The Arrayscan VTI HCS Reader is a high performance modular platform for high content analysis and screening and now features an integrated CrEST X-Light confocal module to providing maximum flexibility for all your biology and cell based assay needs.

Featuring the latest in high-speed Nipkow spinning disk technology and a variable pinhole, you now have finer control over image acquisition across a range of objectives (magnifications) in order to balance image quality and performance for your most demanding cell biology experiments, e.g stem cell colonies, tissues and 3D microenvironments.

Traditional confocal technology is only really of value at higher magnifications, however the variable pinhole technology incorporated into the ArrayScan Confocal Module overcomes this limitation to deleiver the advantages of confocal imaging even at lower magnifications -  ideal for tissues and complex morphologies such as angiogenic tubes, neurons and stem cell colonies.

Uniquely the ArrayScan Confocal Module is also integrated with our 4-color LED Light Engine, bringing robust, laser-like performance without the complications and cost of lasers and the need for alignment of camera, confocal and laser. This unique solid-state light source coupled to the variable pinhole confocal module and integrated into the world’s most productive high-content platform is truly designed to meet the demands of your most challenging high content assays.

Capabilities

• The CrEST X-Light incorporates the latest generation high-speed Nipkow spinning disk
• Software-controlled switching between 40μm and 70μm pinholes for low- and high- NA flexibility
• Robust long-life, four-color Illumination using LED Light Engine technology for laser-like performance and unparalleled ease of use
• User-definable z-range with 0.1μm resolution step size for confocal slices
• Multiple options for 3D projections including new software for enhancing widefield imaging capabilities

Benefits

• Proven – Advanced technology with proven history from the industry leader
• Flexibility – Multiple pinhole and projection options, allowing for enhanced multi-dimensional imaging capabilities
• Simple – No laser alignment and a simple confocal setup allow you to investigate and scan using multiple modes as needed by your biology
• Quality – unique solid-state illumination and high-efficiency filters create a long-life, robust solution with little downtime and lowered cost of ownership
• Compatible – Protect the investment in your current ArrayScan VTI HCS Reader with the field retrofittable confocal module

Deeper Biological Insights

With the ArrayScan VTI HCS Reader and integrated X-Light Confocal Module, multidimensional structures can be imaged more clearly, yielding more detailed information and deeper understanding about biological change. Multiple projection options for image analysis along with the ability to save the stack of images to create 3D movies permits you to investigate both thick and thin cell samples like never before.

Specifications

• Dimensions: Total footprint of the ArrayScan VTI HCS Reader with Confocal Module (D 38.1”(W)34.5”(H)20”
• Confocal Module: 10,000RPM Dual Patterned Nipkow Spinning Disk
• Pinholes: 40μm and 70μm software switchable
• Illumination: Pre-aligned four-color LED Illumination (Excitation 386nm/23, 485nm/20, 549nm/15, 650nm,13)
• Software: Compatible with Thermo Scientific iDEV Workflow Software, Thermo Scientific CellomicsONE BioApplication Portfolio and Thermo Scientific HCI Software (Store 1.5 and above)

Datasheets (1)

Attachments:

ArrayScanStemCellColonies_AppNote.pdf	[Optimizing the high-content analysis of cell morphology using multi-dimensional imaging on the Thermo Scientific ArrayScan Infinity HCS Reader – Part 1 – Stem Cell Colonies]
Confocal Spec Sheet	[Confocal Spec Sheet]