2012 Cellome Award Winner.

This year our winner is Gabor Foldes working in the lab of Sian Harding’s team at Imperial College’s National Heart & Lung Center in the UK has established a model for studying hypertrophy in hESC Cardiomyocytes which will have an impact in cardiac pathology studies, cardiotoxicity assessment as well as drug discovery. High-content measurements of hypertrophy using the Arrayscan* VTI HCS Reader form the basis of this model and would allow the model system to be used at high-throughput to investigate cardiac pathologies, screen for cardiac modulating drugs as well as test the toxicity of compounds in a more relevant system. This paper and Gabor Foldes are our 2012 Cellome Award Winner. click the Learn More button to link to the paper.

Földes G, Mioulane M, Wright JS, Liu AQ, Novak P, Merkely B, Gorelik J, Schneider MD, Ali NN, Harding SE. Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy? J Mol Cell Cardiol. 2011 Feb;50(2):367-76. Epub 2010 Nov 1.